.45 ACP, without doubt . . .
Lots of good information here -- with more to follow, no doubt -- supporting the .45 ACP.
I will add one strictly non-scientific and non-analytic observation: Just this weekend, I took my two favorite carry handguns (a full-size Springfield 1911A1 TRP and a Ruger, four-inch barrel GP-100) to our indoor range for extensive firing sessions. The targets were nine-inch paper plates. It is amazing how much larger the ~11mm hole (from the .45 ACP) appears when compared to the ~9mm perforation from a .38 Special or a .357 magnum.
That increment is the basis for a greater wound cavity, which is clearly an important wound/incapacity parameter.
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