Having tried the .44 with a Speer shot capsule, I loaded up some .45 Colt. I used two 45 cal Walter's wads over 8.0 grains of SR7625, #9 shot (weighed out at 154 grains - 205 shot), and one wad over the shot. A good roll crimp.
It shot virtually as well as the .44 load. This was from a Ruger Vaquero 4.5" barrel:
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If you examine the pattern, you can see the beginning of the spin effect as one side of the pattern (16" wide) has more shot, though density is pretty good in any case.
Between this one and the other, the pattern opens at about three inches a yard (SG cyl is two per yard nominal.)
Pete